The Human Genome Project :: Science Genetics Papers

The kind Genome ProjectImagine having the recipe to make a human being. Knowing its entire genetic make-up from incurning to end. Sounds further more or less fetched, well it isnt with the latest scientific achievements in sequencing the Human Genome. Its only a question of how far we get out take this info to get an understanding of its full potential.The BeginningsLong before there was a formal Human Genome Project (HGP), the Department of Energy (DOE), the National bestow of Health (NIH) and some of their predecessor agencies were interested in developing more than sensitive methods to detect changes in our genetic make-up, induced by ionizing radiation, and to begin understanding the related health effects due to this type of exposure. It has been realise for some time that the genetic-information containing deoxyribonucleic acid (DNA) is the molecule in the cell that is the most sensitive to the effects of radiation and other pollutants, even at lowly levels. One can on ly begin to imagine the impact it will have, in the pharmaceutical, and medical fields as well as how query will change, once we have our complete genetic make-up spelled out.(www.ornl.gov/hgmls/publicat/ adjudicate/aren.html)In 1984, researchers got together at a conference to discuss a single question. The question being asked was if modern DNA research provided an nice way of detecting genetic mutations. Particularly, if there was sufficient evidence to refer an increasing mutation rate in those people and their descendants, who survived the Hiroshima and Nagasaki bombings. The overwhelming finale was, not yet, and so this was the underlying question-answer series that sparked the idea for the formation of the Human Genome Project. (www.ornl.gov/hgmis/publicat/tko/01_forword.html)In 1988, the DOE and the NIH signed a memorandum connexion them in a combined effort to sequence the human genome. hence just two years later, on October 1, 1990 the official clock began reckoning down, signaling the journey and adventure to sequence the entire human genome. (New England journal of Medicine, July 1, 1999)It was evident that once this project was completed it would furnish a highly detailed and accurate genetic reference guide that others could use to get up on, without having to repeat the sequencing process from scratch. Originally the goal of the project was to have a completely sequenced genome within15 years. Due to improved sequencing techniques and the increased competition generated by the hole-and-corner(a) sector, a highly accurate version of the human genome is set to be completed by the year 2003.